Symbol
Name
ID

Bcl6
B cell leukemia/lymphoma 6
MGI:107187

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased B cell proliferation

small thymus

spleen hyperplasia

abnormal blood cell morphology/development

abnormal somatic hypermutation frequency

abnormal T follicular helper cell differentiation

decreased bone marrow cell number

increased eosinophil cell number

decreased germinal center B cell number

absent germinal center B cells

decreased T follicular helper cell number

abnormal memory B cell morphology

abnormal spleen morphology

spleen hypoplasia

absent spleen germinal center

abnormal B cell physiology

decreased IgG level

decreased IgM level

abnormal memory B cell physiology

abnormal T-helper 2 physiology

Availability

Mouse Genotype

Bcl6^tm1.1Toka/Bcl6^tm1.1Toka

Bcl6^tm1Htno/Bcl6^tm1Htno

Bcl6^tm1Rdf/Bcl6^tm1Rdf

Bcl6^tm1Sdt/Bcl6^tm1Sdt

Bcl6^tm2Rdf/Bcl6^tm2Rdf

Bcl6^tm1.1Dent/Bcl6^tm1.1Dent
Tg(Cd4-cre)1Cwi/0 (conditional)

Bcl6^tm1.1Mtto/Bcl6^tm1.1Mtto
Cd79a^tm1(cre)Reth/Cd79a⁺ (conditional)

Bcl6^tm1.1Mtto/Bcl6^tm1.1Mtto
Ighg1^tm1(cre)Cgn/Ighg1⁺ (conditional)

Bcl6^tm1.1Mtto/Bcl6^tm1.1Mtto
Tg(Cd4-cre)1Cwi/0 (conditional)

Bcl6^tm1.1Mtto/Bcl6^tm1.1Mtto
Cd79a^tm1(cre)Reth/Cd79a⁺
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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